When you send an email to any list, ClickUp create a task and put Creator Email (Sender Email) at top of description task field.
We consider very interesting the possibilitie to create an automation with Creator Email if example IT Support department.
When The customers send an email to mailbox, the mailbox resend the email to ClickUp.
The email arrives to ClickUp and at this point with a pre-set automation created, ClickUp send an email to the Creator Email (customer) informing that we receive their request and we work on this asap.